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    HEMLIBRA

     

     

    For routine prophylaxis of bleeding episodes in patients of all ages with congenital haemophilia A, classified as severe or with Factor VIII (FVIII) inhibitors1

    • HEMLIBRA®▼ (emicizumab)
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    1. Roche Medicines
    2. Rare Diseases
    3. HEMLIBRA®▼ (emicizumab)
    4. Dosing
    HEMLIBRA Dosing

    HEMLIBRA is a subcutaneous injection given every week, 2 weeks or 4 weeks1

    HEMLIBRA has three dosing options, giving patients that ability to choose, based on their preferences

    • Initiation dose is 3.0 mg/kg/QW for 4 weeks, for all patients1
    • Maintenance dose options are 1.5 mg/kg/QW, 3.0 mg/kg/Q2W or 6.0 mg/kg/Q4W for all patients1
    HEMLIBRA is a subcutaneous injection given  every week, 2 weeks or 4 weeks

    *Bypassing agents (BPAs) should be discontinued the day before initiating HEMLIBRA.1

    **FVIII prophylaxis may be continued for the first 7 days of HEMLIBRA.1

    • How to calculate the HEMLIBRA dose and total volume for subcutaneous injection¹

      *Do not exceed 2 ml HEMLIBRA solution, per injection.1

      Patient weight (kg) x dose (1.5, 3.0 or 6.0 mg/kg) = total dose (mg).1

      Total dose (mg) ÷ vial concentration (30 or 150 mg/ml) = total injection volume (ml).1

     

    Individualised dosing with single-use vials1

    • There are four vials with different coloured lids, and two different concentrations (30 mg/ml and 150 mg/ml)1
    • Do not combine the 30 mg/ml vial with other concentrations of HEMLIBRA in the same injection1

    For full details please refer to the HEMLIBRA® Summary of Product Characteristics.

    BPA, bypassing agent; FVIII, Factor VIII; QW, every week; Q2W, every 2 weeks; Q4W, every 4 weeks.

    References:

    1. HEMLIBRA Summary of Product Characteristics.

    M-GB-00001031

    Date of preparation: August 2020

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