Learn more about TECENTRIQ®▼ (atezolizumab), a cancer immunotherapy treatment, by clicking on the respective indication of interest:

 

HCC

Lung

TNBC

Hepatocellular carcinoma1,2

Tecentriq®, in combination with Avastin® (bevacizumab), is indicated for the treatment of adult patients with advanced or unresectable hepatocellular carcinoma (HCC) who have not received prior systemic therapy.
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Non-small cell lung cancer (NSCLC):1-2

Tecentriq is indicated as 1L monotherapy for adult patients with metastatic non-small cell lung cancer (NSCLC ) whose tumours have a PD- L1 expression ≥ 50 % tumour cells (TC ) or ≥10% tumour-infiltrating immune cells (IC ) and who do not have EGFR mutant or ALK- positive NSCLC.
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Tecentriq®, in combination with Avastin® (bevacizumab), paclitaxel and carboplatin, is indicated for the first-line treatment of adult patients with metastatic non-squamous non-small cell lung cancer (NSCLC). In patients with EGFR mutant or ALK-positive NSCLC, Tecentriq®, in combination with Avastin® (bevacizumab), paclitaxel and carboplatin, is indicated only after failure of appropriate targeted therapies.

Tecentriq® as monotherapy is indicated for the treatment of adult patients with locally advanced or metastatic NSCLC after prior chemotherapy. Patients with EGFR mutant or ALK-positive NSCLC should also have received targeted therapies before receiving Tecentriq®.

Tecentriq®, in combination with nab-paclitaxel and carboplatin, is indicated for the first-line treatment of adult patients with metastatic non-squamous NSCLC who do not have EGFR mutant or ALK-positive NSCLC

Small cell lung cancer (SCLC):1,2

Tecentriq®, in combination with carboplatin and etoposide, is indicated for the first-line treatment of adult patients with extensive-stage small cell lung cancer (ES-SCLC).
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Triple-negative breast cancer (TNBC):1,2

Tecentriq® in combination with nab-paclitaxel is indicated for the treatment of adult patients with unresectable locally advanced or metastatic triple-negative breast cancer (TNBC) whose tumours have PD-L1 expression ≥ 1% and who have not received prior chemotherapy for metastatic disease. 
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Urothelial carcinoma (UC): 1,2

Tecentriq® as monotherapy is indicated for the treatment of adult patients with locally advanced or metastatic urothelial carcinoma:

  • after prior platinum-containing chemotherapy, or
  • who are considered cisplatin ineligible, and whose tumours have a PD-L1 expression ≥ 5%

 

References:

  1. Tecentriq Summary of Product Characteristics – Great Britain
  2. Tecentriq Summary of Product Characteristics – Northern Ireland


M-GB-00004351.
Date of preparation: July 2021